Mobile phone-based microscopy for blood cell imaging and count applications.

Date

10-2011

Degree

Bachelor of Science in Applied Physics

College

College of Arts and Sciences (CAS)

Adviser/Committee Chair

Lou Serafin M. Lozada

Abstract

The amount of white blood cells (WBC) and red blood cells (RBC) in the body is an essential indicator for disease diagnosis and management. However, eye count can often be unreliable, and the required microscope is either inefficiently portable or prohibitive. Fortunately, increase in access to mobile phone networks suggests the possibility of using portable, camera-enabled mobile phones for diagnostic imaging and telemedicine. Towards this end, a compact microscopy attachment to commercial mobile phones was designed and constructed. Its diagnostic potential was demonstrated by Imaging WBC and RBC in diluted and stained samples, and by facilitating WBC count. e device is a three-lens system composed of an objective and an eyepiece aligned to the phone camera. Unlike conventional light microscope, it does not utilized any illumination-conditioning system and as a result, produces relatively less sharper images. In spite of this, the device attained that necessary to distinguish blood cells and their morphology, as well as the counting grids necessary for cell count applications. A 5% difference between the prototype's WBC count and a standard microscope count is revealed to be sufficiently enough for the device to replace or be used interchangeably with the regular light microscope in performing WBC counts. Keywords: 42.15.Eq Optical system design, 87.64.M- Optical microscopy, 83.80.Lz Physiological materials

Language

English

Location

UPLB Main Library Special Collections Section (USCS)

Call Number

Thesis

Document Type

Thesis

This document is currently not available here.

Share

COinS