Erythromycin production of Saccharopolyspora erythraea Atcc 11635 using local substrates.

Date

3-1992

Degree

Bachelor of Science in Biology

College

College of Arts and Sciences (CAS)

Adviser/Committee Chair

Asuncion K. Raymundo

Abstract

Different types of media such as Tryptic Soy Broth (TSB), locally formulated medium (LFM4) and erythromycin production medium (EM) were tried as media for erythromycin production for Saccharopolyspora erythraea . TSB appeared to be a good basal medium to use for erythromycin production since it gave the highest yield in comparison to the other media. Substitution of glucose as carbon source with molasses and brown sugar was done in TSB. Maximum erythromycin yield in the three media did not vary significantly from each other. Peak of production occurred after 144 hours of fermentation within the pH range of a.25—S.3. Molasses appeared to be a better carbon source for erythromycin production since it is much cheaper while having a yield was comparable with those obtained with the other carbon source.

Language

English

Location

UPLB Main Library Special Collections Section (USCS)

Call Number

Thesis

Document Type

Thesis

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