Cytogenetic effects of narra (Pterocarpus indicus Willd.) bark extract on human leukocytes in vitro.
Date
3-2003
Degree
Bachelor of Science in Biology
Major Course
Major in Ecology Genetics
College
College of Arts and Sciences (CAS)
Adviser/Committee Chair
Adelina A. Barrion
Abstract
Cytogenetic study was conducted to test the effects of three treatments (weight by volume): 1%, 3% and 5% of narra (Plerocarpus indicus Willd.) bark extract on in vitro cultures of human leukocytes from five male blood donors. Statistical analysis using repeated measure design and Duncan's Multiple Range Test (DMRT) showed that Giemsa-stained cells exhibited significant differences in mitotic indices. With the increasing concentrations of treatments was the corresponding significant decreasing trend of mean mitotic index: 0.084 (1%), 0.059 (3%), 0.032 (5%) while the Control was 0.12. Otherwise is true of the chromosomal aberrations wherein the increasing concentrations of treatments corresponding with significantly increasing frequencies of highly condensed chromosomes 0.027 (1%), 0.25 (3%), and 0.48 (5%), the Control was 0.19, chromosome gaps 0.12 (1%), 0.23 (3%) and 0.30 (5%), the Control was 0.10, breaks 0.19 (1%), 0.31 (3%) and 0.28 (5%), the Control was 0.096 and loosely paired sister chromatids 0.15 (1%), 0.15 (3%) and 0.23 (5%), the Control was 0.062. The control exhibited spontaneous chromosomal aberrations.
Language
English
Location
UPLB Main Library Special Collections Section (USCS)
Call Number
Thesis
Recommended Citation
Baria, Maria Vanessa B., "Cytogenetic effects of narra (Pterocarpus indicus Willd.) bark extract on human leukocytes in vitro." (2003). Undergraduate Theses. 10794.
https://www.ukdr.uplb.edu.ph/etd-undergrad/10794
Document Type
Thesis
