Effects of lagundi (Vitex negundo) crude extract of some reproductive parameters of adult male laboratory rats.

Date

6-1992

Degree

Bachelor of Science in Biology

Major Course

Major in Cell Biology

College

College of Arts and Sciences (CAS)

Adviser/Committee Chair

Pablo P. Ocampo

Abstract

The effects of lagundi (Vitex nequndo) crude extract on some reproductive parameters of mature male laboratory rats were evaluated. Crude hexane extracts of lagundi leaves were administered to the rats by gavage techniques. Lagundi crude extract caused a significant decrease in sperm and motility and sperm count and rats treated with high moderate extract concentrations had significantly higher testicular weights. However, the crude extract had no apparent effects on body weights, sperm morphology, and epididymal weight. Histo-pathological examination testicular sections revealed that lagundi crude extract caused marked interstitial fluid accumulation and spermatogenic arrest. Testicular damage in one of the animals under the high dose treatment revealed sever degeneration of the seminiferous tubules and interstitial fluid accumulation.

Language

English

Location

UPLB Main Library Special Collections Section (USCS)

Call Number

Thesis

Document Type

Thesis

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