The cytogenetic effects of Artemisia vulgaris L. (Asteraceae/Compositae) aqueous leaf extract on human leukocytes in vitro

Date

3-1997

Degree

Bachelor of Science in Biology

Major Course

Major in Cell Biology

College

College of Arts and Sciences (CAS)

Adviser/Committee Chair

Mendioro M. S.

Abstract

BSTRACT GRUEZO, KRISHLEX ANTHONY G University of the Philippines Los Banos, March 1997. The Cytogenetic Effects of Artemisia vulgaris L. Asteraceae/Compositae) Aqueous Leaf Extract on Human Leukocytes In vitro. Undergraduate thesis, B.S. Biology (Cell Biology), ADVISER: Mendioro, M.S., Ph.D. Leukocytes from two male subjects were cultured and treated with one, three and five percent aqueous leaf extract (ale.) of Artemisia vulgaris L. (Asteraceae/Compositae) while one culture served as control and received only sterile isotonic saline solution. Using Duncan's Multiple Range Test (DMRT), results of the treatment showed a significant depression of the mitotic indices of the treated cultures (mean mitotic indices: control = 0.1655; 1% a.l.e. = 0 0820; 3% a.l.e = 0.0435; 5% a.l.e = 0.0175) and significantly increased occurrence of condensed chromosome sets (control = 0.0500; 1% a.l.e.= 0.1600; 3% a.l.e = 0.3200). No significant differences on frequencies of chromosomal aberrations, namely: gaps (control = 0.1000; 1% a.l.e.= 0.2333; 3% ale. = 0.2168), breaks (control = 0.0000; 1% a.l.e.= 0.0167; 3% a.l.e. = 0.0500) and loose sister chromatids (control = 0.2333; 1% a.l.e.= 0.2667; 3% a.l.e. = 0.3333) were observed. Based on these results, it is recommended that aqueous leaf extract of Artemisia vulgaris L. (Damong maria) should be orally taken at relatively low dosage irrespective of ailments.

Language

English

Location

UPLB Main Library Special Collections Section (USCS)

Call Number

Thesis

Document Type

Thesis

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