"Histological analysis of F7 rats (Rattus rattus mindanensis Linnaeus) " by Nievelyn S. Ocampo

Histological analysis of F7 rats (Rattus rattus mindanensis Linnaeus) generated from survivors of sustained baiting with warfarin

Date

3-1994

Degree

Bachelor of Science in Biology

Major Course

Major in Cell Biology

College

College of Arts and Sciences (CAS)

Adviser/Committee Chair

Rita P. Laude

Abstract

Comparative histological analysis of liver, kidney, spleen and ovary of F7 survivors of sustained baiting with anticoagulant - Warfarin and their control was done to determine the histological effect of Warfarin. Analysis showed that the most observable morphological abnormality was necrosis as evidenced by the occurrence of pyknotic nucleus and intense acidophilic cytoplasm. Degeneration of tissues ranging from mild to moderate were also noted. Sinusoidal congestion and hemorrhages were also observed but not for all damaged organs. The survival of rats from parentals down to F7 generation and tissue changes exhibited by F7 rats indicates the survivor's capacity to sustain such tissue damage.

Language

English

Location

UPLB Main Library Special Collections Section (USCS)

Call Number

Thesis

Document Type

Thesis

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