The cytogenetic effect of the antihypertensive agent reserpine (Serpasil) on human leukocytes cultured in vitro

Date

3-1982

Degree

Bachelor of Science in Biology

College

College of Arts and Sciences (CAS)

Adviser/Committee Chair

Liwayway M. Engle

Abstract

Leukocytes from five male and five female volunteers were treated with four reserpine concentrations: 0, 1, 1. 67, 2. 5, and 5 ug/ml. Treatment resulted in a decrease in mitotic index and increased chromosome condensation. No significant effect on chromosomal aberrations such as gaps, breaks, and loose sister chromatid pairing as well as theploidy level of the cell was observed. The probable implications of the observed results were discussed.

Language

English

Location

UPLB Main Library Special Collections Section (USCS)

Call Number

Thesis

Document Type

Thesis

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