Preliminary study on the hematologic profile, renal function and ultrasonogram features in adult dogs given cholesterol with or without nanoliposome-encapsulated malunggay (Moringa oleifera) administration

Date

6-2015

Degree

Doctor of Veterinary Medicine

College

College of Veterinary Medicine (CVM)

Adviser/Committee Chair

Marianne Leila S. Flores

Co-adviser

Evelyn B. Rodriguez

Abstract

Studies on the hematology, renal function and ultrasonogram features in adult dogs given nanoliposome-encapsulated malunggay (Moringa oleifera) phenolic extract have not yet been done and it was described in this study. Six (6) adult dogs were divided into three groups: one control group (Group A: cholesterol only) and two treatment groups (Group B: cholesterol with malunggay phenolic extract Group C: cholesterol with nanoliposome-encapsulated malunggay phenolic extract) with two dogs per group. Each dog was subjected to a complete blood count and renal ultrasonography at weeks 0, 1, and 5. Kidney function test was also done at weeks 0 and 5. The results showed that thrombocytopenia and a decrease in the elevated blood urea nitrogen level were observed after administration of the nanoliposome-encapsulated malunggay phenolic extract. It also showed that the renal echo mean values of dogs C1 and C2 decreased, except for the renal pelvis of dog C2 which increased, at week 5. This suggests that nanoliposome-encapsulated malunggay phenolic extract may have an effect on the platelets and kidneys. However, further studies should be done to verify this association.

Language

English

Location

UPLB College of Veterinary Medicine (CVM)

Call Number

LG 993.5 2015 V4 M35

Document Type

Thesis

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