Effects of probiotics (Bacillus subtilis QST 713), acidifier and antibiotic (Zinc bacitracin) on the histopathology and morphometry of the jejunum of broiler chickens challenged with Salmonella enteritidis and Clostridium perfringens

Date

6-2015

Degree

Doctor of Veterinary Medicine

College

College of Veterinary Medicine (CVM)

Adviser/Committee Chair

Benjamin Reuel G Marte

Abstract

Effects of probiotics (Bacillus subtilis QST 713), acidifier and antibiotic (zinc bacitracin) on the histopathology and morphometry of the jejunum of broiler chickens with bacterial challenge were evaluated and determined using 392 day old chicks of mixed sexes randomly divided to seven treatment groups. Salmonella enteritidis (106 cfu/ml) and Clostridium perfringens (109 cfu/ml) were given orally at day 19, 20 and 21 then jejunal tissue sample were collected on day 26 and 37. Histopathologically between challenged groups, congestion, hemorrhage and necrosis lesion scores were least on broilers given with probiotics at day 26 and antibiotic at day 37. On jejunal morphometry, probiotics with acidifier increased mucosal thickness (p < 0.05), villus height (p < 0.01) and villus volume (p < 0.01) at day 26 and increased villus width (p < 0.01) and villus volume (p < 0.01) at day 37. Probiotics given alone as compared to antibiotic significantly increased mucosal thickness (p < 0.05) and villus height (p < 0.01) at day 26 but no difference were present at day 37. This study suggests that probiotics given alone or with acidifier can substitute antibiotic to improve animal health in relation to an improved villi morphometry.

Language

English

Location

UPLB College of Veterinary Medicine (CVM)

Call Number

LG 993.5 2015 V4 F56

Document Type

Thesis

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