Comparison of the effects of probiotic (Bacillus subtilis QST 713), acidifier and antibiotic treatments on the jejunal gross lesions in broiler chicken infected with Clostridium perfringens and Salmonella enteritidis

Date

6-2015

Degree

Doctor of Veterinary Medicine

College

College of Veterinary Medicine (CVM)

Adviser/Committee Chair

Hope G Rovira

Abstract

Three hundred and ninety-two day old Cobb-500 broiler chickens of mixed sexes were randomly divided into 7 treatments with 4 replicates each (14 birds/replicate). Birds in treatment 1 were kept as negative controls while those in treatment 2 were positive controls which received no medication and were challenged with Clostridium perfringens and Salmonella enteritidis. This study was conducted to determine the effect of probiotic (Bacillus subtilis QST 713) on the jejunal gross lesions caused by enteric bacteria. However, comparisons to other treatments were included: rations containing zinc bacitracin (Treatment 3 and 7) and combination of probiotic and acidifier (Treatment 6). Birds in treatment 2, 3, 5 and 6 were challenged orally on day 19 with 1 ml broth culture of C. perfringens (109 CFU/ml) and S. enteritidis (106 CFU/ml) followed by via drinking water on day 20 and 21. Necropsy focused on jejunal lesion scores on day 26 and 37. The probiotic and antibiotic treatments showed reduced effectiveness on day 37 however potential synergism between probiotic and acidifier was observed. Result present no significant (p > 0.05) difference on the gross jejunal lesion scores among treatment groups, as none of the feed additives effectively reduced the jejunal gross lesions.

Language

English

Location

UPLB College of Veterinary Medicine (CVM)

Call Number

LG 993.5 2015 V4 C37

Document Type

Thesis

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