Cytogenetic effects of selected plants known to treat diabetes on human leukocytes cultured in vitro

Abstract

Aqueous extracts from the cloves of Allium sativum L. (garlic), seeds of Swietenia macrophylla King (mahogany), and leaves of Lagerstroemia speciosa L. (banaba) were tested on human leukocytes cultured in vitro. Mean mitotic indices of the leukocytes were reduced significantly by S. macrophylla and L. speciosa but not by A. sativum. The three medicinal plants did not significantly induce chromosomal abnormalities such as gaps, breaks, and loose sister chromatids. S. macrophylla significantly induced chromosome condensation from 16.4% to 78.4%; L. speciosa from 12% to 73.5%.

Source or Periodical Title

Philippine Agricultural Scientist

ISSN

317454

Page

19-24

Document Type

Article

Subject

Allium sativum, Cytogenetic effects, Diabetes, Human leukocytes, Lagerstroemia speciosa, Medicinal plants, Swietenia macrophylla

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