Lipid metabolism in immunized Brown Norway rats fed with different dietary proteins

Abstract

Feeding trials on immunized Brown Norway (BN) rats were conducted to test the effect of 3 different dietary protein sources on lipid metabolism. Results revealed that immunization did not seem to affect the cholesterol metabolism in BN rats. There were no significant differences in weight gain, food efficiency, liver weight, relative liver weight and spleen weight. However, the weight of perirenal adipose tissues of UDF-fed rats was found to be significantly lowest among the groups. Liver cholesterol, hepatic triglyceride and serum triglyceride levels were significantly low in SOY-and UDF-fed rats, while cholesterol, HDL-cholesterol and phospholipid levels in the serum were not found to be significantly different. Fecal excretion, which was observed to be significantly high in UDF-fed rats, was attributed to the interference of UDF with the intestinal absorption of neutral and acidic steroids thus decreasing cholesterol absorption.

Source or Periodical Title

Philippine Agricultural Scientist

ISSN

317454

Page

73-81

Document Type

Article

Subject

Brown Norway rats, Cholesterol metabolism, Cholesterol-lowering effect, Lipid metabolism, Protein source, Undigested fraction of soybean

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