Pantherinine, a cytotoxic aromatic alkaloid, and 7-deazainosine from the ascidian Aplidium pantherinum

Abstract

A new cytotoxic aromatic alkaloid, pantherinine [1], and a mixture of nucleosides including 7-deazainosine [3] have been isolated from the ascidian Aplidium pantherinum collected at Stenhouse Bay, South Australia. The structures were determined primarily from 1H and 13C-nmr data, especially one-bond and multiple-bond proton-carbon correlations. Although 7-deazainosine [3] has been known as a synthetic compound for several decades, this appears to be the first report of its isolation as a natural product. © 1993, American Chemical Society. All rights reserved.

Source or Periodical Title

Journal of Natural Products

ISSN

1633864

Page

1813-1816

Document Type

Article

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