Phaeanthine-2′α-N-oxide and pycmanilline, new bisbenzylisoquinoline alkaloids from Pycnarrhena manillensis

Creator

Jacinto C. Regalado, University of the Philippines Los Banos
Cong yuan Gao, Peking University Health Science Center
Emil Fu, Sandoz International GmbH
Fu tyan Lin, University of Pittsburgh
Mei chao Lin, University of Pittsburgh
Lan K. Wong, University of Pittsburgh
Paul L. Schiff, University of Pittsburgh

Abstract

Chromatography of an ethanolic extract of Pycrarrhena manillensis over silica gel afforded phaeanthine-2′α-N-oxide (1) and pycmanilline (2) which were characterized as new bisbenzylisoquinoline alkaloids by a consideration of physicochemical data and the utilization of simple chemical reactions. Phaeathine-2′α-N-oxide (1) was reduced to phaeanthine (3) while pycmanilline (2), a secobisbenzyliso-quinoline alkaloid, was prepared via oxidation of phaeanthine (3). © 1987.

Source or Periodical Title

Heterocycles

ISSN

3855414

Page

2573-2578

Document Type

Article

Recommended Citation

Regalado, Jacinto C.; Gao, Cong yuan; Fu, Emil; Lin, Fu tyan; Lin, Mei chao; Wong, Lan K.; and Schiff, Paul L., "Phaeanthine-2′α-N-oxide and pycmanilline, new bisbenzylisoquinoline alkaloids from Pycnarrhena manillensis" (2021). Journal Article. 3727.
https://www.ukdr.uplb.edu.ph/journal-articles/3727