Localization of secreted ferritin (FER2) in the embryos of the tick Haemaphysalis longicornis

Creator

Emmanuel P. Hernandez, College of Veterinary Medicine, University of the Philippines Los Baños
Kei Shimazaki
Hiroko Niihara
Rika Umemiya‑Shirafuji
Kozo Fujisaki
Tetsuya Tanaka

Issue Date

1-2023

Abstract

Despite the absence of a blood meal, embryogenesis involves many processes that require nutrients and other essen‑ tial elements, including iron. Due to the lack of an external source of these nutrients, these requirements are acquired maternally. Because of the toxic nature of iron, they are transferred through iron transport molecules such as secreted ferritin (FER2). Here we tried to follow the trail of the FER2 through indirect immunofuorescence, and we observed an apparent shift of FER2 from the germ layer at the early part of development to the appendages during the late stage of embryogenesis. FER2 is also found in the middle part of the legs of the embryo. The apparent movement not only sheds light on iron processing events during embryogenesis but also indirectly guides organogenesis in the tick.

Source or Periodical Title

Parasites & Vectors

Volume

16

Issue

42

Page

1-5

Document Type

Article

College

College of Veterinary Medicine (CVM)

Recommended Citation

Hernandez, Emmanuel P.; Shimazaki, Kei; Niihara, Hiroko; Umemiya‑Shirafuji, Rika; Fujisaki, Kozo; and Tanaka, Tetsuya, "Localization of secreted ferritin (FER2) in the embryos of the tick Haemaphysalis longicornis" (2023). Journal Article. 5772.
https://www.ukdr.uplb.edu.ph/journal-articles/5772