Genetic characterization and phylogenetic analysis of infectious bursal disease virus from commercial broiler flocks in the Philippines

Issue Date

7-2022

Abstract

Infectious bursal disease (IBD) is a highly contagious immunosuppressive disease of poultry. To better understand the epidemiology of IBD virus (IBDV) in the country, a total of 39 field IBDVs from commercial broiler flocks in seven regions of the Philippines were analyzed. Clinical signs observed were uniformity problems, inappetence, lethargy, stunted growth, poor average daily gain, irregular size of bursa of Fabricius, and mortality rates ranging from four to 19%. Phylogenetic analysis highlighted the following: three (7.69%) field strains were from G1 classic genotype; 16 (41.03%) were G1 vaccine IBDVs; 17 (43.59%) were G2 variants; two (5.12%) were G3 vvIBDVs; and one (2.56%) was a G7 vaccine IBDV. Regional distribution showed that G1 IBDVs were detected in regions 2, 3, 4, 5, 6, 7, and 11, G2 IBDVs were observed in Regions 3 and 4, G3 IBDVs in Regions 6 and 7, and G7 IBDV in Region 3. It was demonstrated that G2 IBDVs were closely related (95-96%) to variant strains from the USA, whereas the G1 and G3 IBDVs were closely related (96.00-100%) to IBDVs from several countries in Southeast and Far East Asia. This study is so far the first to comprehensively document the molecular as well as the epidemiological characteristics of IBDVs in the Philippines.

Source or Periodical Title

Philippine Journal of Veterinary Medicine

ISSN

0031-7705

Volume

59

Issue

2

Page

107-119

Document Type

Article

College

College of Veterinary Medicine (CVM)

Frequency

semi-annually

Physical Description

illustration, map, tables

Language

English

En – AGROVOC descriptors

BROILER CHICKENS; INFECTIOUS BURSAL DISEASE VIRUS; INFECTIOUS DISEASES; PHYLIGENETIC ANALYSIS; PHILIPPINES

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