The laboratory mouse: its origin and uses in biomedical research
Professorial Chair Lecture
Diamond Jubilee Professorial Chair Lecture
Place
UPLB College of Veterinary Medicine Department of Veterinary Microbiology, Pathology and Public Health
Date
1995
Abstract
The laboratory mouse, Mus musculus, is the most popularly used animal among the rodent group of laboratory animals. It satisfies all the three good characteristics of an ideal laboratory animal, i. e. acceptability, availability and affordability. However its exact origin was A very controversial issue among researchers. This controversy was settled once and for all when the group of Dr. Moriwaki from the National Institute of Genetics, Japan made an in-depth genetic study of several indigenous wild population of mice from different parts of the world. Aside from morphological and biochemical studies the group made molecular analysis of its DNA and other specific genes that traced the evolutionary origin of the laboratory mouse. It was concluded that the laboratory mouse originated from female European mouse with introduction of some nuclear genome from male Asian mouse.
The laboratory mouse is mostly used in researches in genetiics, immunology, pharmacology, physiology, virology, pathology, toxicology, and theriogenology.
Location
UPLB Main Library Special Collections Section
Call Number
Sp. Col.
Recommended citation
Masangkay, Joseph S., "The laboratory mouse: its origin and uses in biomedical research" (1995). Professorial Chair Lecture. 97.
https://www.ukdr.uplb.edu.ph/professorial_lectures/97
Pages/Collation
11 leaves