Effects of lagundi (Vitex negundo L.) leaf extract on the internal organs of white mice (Mus Musculus Balb

Date

10-1985

Degree

Bachelor of Science in Biology

College

College of Arts and Sciences (CAS)

Adviser/Committee Chair

Ludivina S. De Padua

Abstract

A study was undertaken using twelve 3i—month old male mice ( Mus musculus BALB/C) to determine the effects of varying concentrations of Lagundi ( Vitex negundo L.) leaf extract on the internal organs of white mice using gross morphological and histological parameters. Three treatment groups were evaluated, namely: distilled water, 10% lagundi leaf extract and 20% lagundi leaf extract in distilled water, over a period of four weeks. The lagundi leaf extract treatments did not cause any significant effect on the weights (expressed in mg/gm body weight) of the internal organs (liver, kidneys, spleen, testis, small and large intestine, heart, adrenal gland and pituitary gland) studied. It was observed that 0.25 ml of 10% lagundi leaf extract given daily for four weeks through the gavage method does not cause any abnormality in the internal organs of white mice. However, significant effects such as karyorhexis,

Language

English

Call Number

Thesis

Document Type

Thesis

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