Preliminary study on the effects of sodium nitrite on guinea pig (Cavia porcellus) liver mitochondrial dehydrogenase activity

Date

3-1984

Degree

Bachelor of Science in Biology

College

College of Arts and Sciences (CAS)

Adviser/Committee Chair

William G. Padolina

Abstract

ABSTRACT JAMIAS, MARTIN A., University of the Philippines Los Banos, April, 1984. Preliminary Study on the Effect of Sodium Nitrite on Guinea Pig (Cavia sp.) Liver Mitochondrial Dehydrogenase Activity .

Adviser; Dr. William Padolina

The study was conducted to determine the effects of sodium nitrite on guinea pig liver mitochondrial succinate dehydrogenase activity which was measured using the dye (DPIP) reduction technique. The liver mitochondrial dehydrogenase activity was enhanced when sodium nitrite was administered in vitro. Sodium nitrite may be oxidized to donate electrons to speed up the dye reduction. In vivo study brought about no sodium nitrite effect on the mitochondrial dehydrogenase activity. This may be due to the dispersion of the compound to various parts of the body, its elimination, and oxidation to nitrate.

Language

English

Location

UPLB Main Library Special Collections Section (USCS)

Call Number

Thesis

Document Type

Thesis

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