Healing activity of gamma-radiated propolisalginate dressing from the Philippine stingless bees (Tetragonula biroi Friese) in full thickness incisional wounds of domestic shorthaired cats

Date

6-2015

Degree

Doctor of Veterinary Medicine

College

College of Veterinary Medicine (CVM)

Adviser/Committee Chair

Amelita C. Estacio

Co-adviser

Therese Marie A. Collantes

Abstract

The wound healing activity of propolis-alginate dressings from the Philippine stingless bees (Tetragonula biroi Friese) on incisional wound was investigated. Eighteen male domestic shorthaired cats aged 1-2 years, were randomly allocated to four groups: non-treated, H2O2+povidone-iodine, fusidate sodium and propolis-alginate. A 3-cm full thickness skinincision was made on the dorsum of each cat and dressings were applied twice daily for 21 days. Wound scoring and size measurement was done. Mean total wound scores (MTWS)andmean duration of healing werecomputed. Skin biopsywas obtained for histopathologic, superficial contraction index (SCI), deep contraction index (DCI), and wound severity index (WSI) assessment.Propolis-alginate treatment resulted in rapid complete healing of incisional wounds exemplified as significantly low MTWS, high percent improvement in MTWS, short wound healingduration and high wound contraction rate.Microscopically, complete re-epithelialization, intact dermal matrix, growth of hair follicles and glands due to high SCI, and DCI and low WSI were observed with propolis-alginate treatment. Cost benefit analysis shows that propolis-alginate treatment is most cost effective. These findings suggest the efficaciousness of propolis-alginate dressing on full thickness incisional wound in cats.

Language

English

Call Number

LG 993.5 2015 V4 T36

Document Type

Thesis

This document is currently not available here.

Share

COinS