Efficacy, mutagenicity and toxicity of trichosetin as a new antibiotic for poultry
Issue Date
6-2007
Abstract
Trichosetin is a new antibiotic produced from the dual culture of Catharanthus roseus callus and Trichoderma harzianum. Experiments were conducted to determine its efficacy and safety as a therapeutic agent for poultry. Antimicrobial assay showed that this antibiotic was inhibitory to a multidrug-resistant strain of Staphylococcus sp. It also exhibited moderate activity against Pasteurella multocida. Toxicity assay showed that it was not toxic to chicken when administered orally at 50 mg kg-1 body weight daily for 1 wk. Mutagenicity assay revealed that it was not mutagenic. These results suggest that trichosetin can be developed as a therapeutic agent for poultry.
Source or Periodical Title
Philippine Agricultural Scientist
ISSN
317454
Volume
90
Issue
2
Page
91-95
Document Type
Article
Language
English
Subject
Antibiotic, Mutagenicity, Poultry, Toxicity, Trichosetin
Recommended Citation
Marfori, Eufrocinio & Malasa, Aubrey. (2007). Efficacy, mutagenicity and toxicity of trichosetin as a new antibiotic for poultry. The Philippine agriculturist. 90. 91-95.
Digital Copy
none